Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable keratin filament binding activity. Acts upstream of or within keratinocyte differentiation; response to radiation; and stem cell differentiation. Located in basal part of cell; cell periphery; and keratin filament. Is active in cornified envelope. Is expressed in several structures, including alimentary system; autopod; genitourinary system; integumental system; and sensory organ. Used to study epidermolysis bullosa simplex and epidermolysis bullosa simplex Dowling-Meara type. Human ortholog(s) of this gene implicated in Naegeli-Franceschetti-Jadassohn syndrome; dermatopathia pigmentosa reticularis; and epidermolysis bullosa simplex. Orthologous to human KRT14 (keratin 14).