Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in JNK cascade and cellular response to anisomycin. Acts upstream of or within several processes, including circulatory system development; positive regulation of cell population proliferation; and regulation of primary metabolic process. Located in nucleus. Part of transcription factor AP-1 complex and transcription repressor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; long bone; and sensory organ. Used to study psoriasis and pulmonary emphysema. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit).
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