Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including fibronectin binding activity; integrin binding activity; and protein heterodimerization activity. Involved in postsynapse organization and synaptic membrane adhesion. Acts upstream of or within several processes, including dendritic spine maintenance; exploration behavior; and negative regulation of Rho protein signal transduction. Located in several cellular components, including basolateral plasma membrane; external side of plasma membrane; and synaptic membrane. Is active in glutamatergic synapse; neuromuscular junction; and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa. Orthologous to human ITGA3 (integrin subunit alpha 3).