Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including lymphocyte differentiation; positive regulation of gene expression; and regulation of peptide hormone secretion. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including cellular response to cytokine stimulus; regulation of gene expression; and salivary gland morphogenesis. Located in external side of plasma membrane. Part of interleukin-6 receptor complex. Is active in extracellular region. Is expressed in several structures, including alimentary system; blastocyst-stage conceptus; genitourinary system; hemolymphoid system; and yolk sac. Human ortholog(s) of this gene implicated in several diseases, including cerebrovascular disease (multiple); depressive disorder (multiple); glucose metabolism disease (multiple); liver disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6).

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Gene Ontology Evidence Code Abbreviations:

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