Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables L-iduronidase activity. Involved in heparan sulfate proteoglycan catabolic process. Acts upstream of or within several processes, including glycosaminoglycan catabolic process; learning or memory; and skeletal system development. Located in extracellular space. Is active in lysosomal lumen. Used to study mucopolysaccharidosis I and otitis media. Human ortholog(s) of this gene implicated in Scheie syndrome; mucopolysaccharidosis I; mucopolysaccharidosis Ih; and mucopolysaccharidosis Ih/s. Orthologous to human IDUA (alpha-L-iduronidase).