Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables neurotransmitter transmembrane transporter activity; nitric-oxide synthase binding activity; and serotonin:sodium:chloride symporter activity. Involved in several processes, including nervous system development; platelet aggregation; and serotonin uptake. Acts upstream of or within cellular response to organic substance. Located in focal adhesion and presynapse. Is expressed in several structures, including early conceptus; liver; nervous system; ovary; and polar body. Used to study autism spectrum disorder and sudden infant death syndrome. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; anxiety disorder (multiple); depressive disorder (multiple); and heart disease (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4).