Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; phospholipase C-activating serotonin receptor signaling pathway; and regulation of corticotropin-releasing hormone secretion. Acts upstream of or within positive regulation of calcium-mediated signaling and positive regulation of fat cell differentiation. Predicted to be located in external side of plasma membrane. Predicted to be part of G protein-coupled serotonin receptor complex. Predicted to be active in dendrite and plasma membrane. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; heart; and sensory organ. Used to study Prader-Willi syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in bipolar disorder; obesity; and schizophrenia. Orthologous to human HTR2C (5-hydroxytryptamine receptor 2C).