Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mesodermal cell fate specification and positive regulation of DNA-templated transcription. Acts upstream of or within several processes, including embryonic morphogenesis; regionalization; and reproductive structure development. Part of protein-DNA complex and transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; limb; limb bud; and skeletal system. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11).