Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables peptide antigen binding activity. Acts upstream of or within several processes, including positive regulation of biosynthetic process; positive regulation of leukocyte mediated cytotoxicity; and response to bacterium. Located in external side of plasma membrane. Part of MHC class Ib protein complex. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and lung. Human ortholog(s) of this gene implicated in asthma and hepatitis C. Orthologous to human HLA-G (major histocompatibility complex, class I, G).