Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission; modulation of chemical synaptic transmission; and regulation of receptor recycling. Predicted to act upstream of or within monoatomic ion transmembrane transport. Located in postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in parallel fiber to Purkinje cell synapse. Is expressed in several structures, including adrenal gland; central nervous system; eye; genitourinary system; and organ of Corti. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 94. Orthologous to human GRIA3 (glutamate ionotropic receptor AMPA type subunit 3).