Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTP binding activity and GTPase activity. Involved in negative regulation of insulin secretion. Acts upstream of with a negative effect on vesicle docking involved in exocytosis. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; dopamine receptor signaling pathway; and locomotory behavior. Located in cell body and dendrite. Is expressed in several structures, including alimentary system; brain; ganglia; genitourinary system; and sensory organ. Used to study developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Orthologous to human GNAO1 (G protein subunit alpha o1).