Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables heparin binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including myoblast migration involved in skeletal muscle regeneration; positive regulation of lamellipodium assembly; and positive regulation of macrophage chemotaxis. Acts upstream of or within cellular response to dexamethasone stimulus; negative regulation of skeletal muscle tissue growth; and transforming growth factor beta receptor signaling pathway. Located in extracellular space. Is expressed in several structures, including abdominal wall; choroid plexus; connective tissue; embryo mesenchyme; and skeletal musculature. Used to study myostatin-related muscle hypertrophy. Human ortholog(s) of this gene implicated in myostatin-related muscle hypertrophy. Orthologous to human MSTN (myostatin).
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