Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Predicted to be involved in gamma-aminobutyric acid biosynthetic process and glutamate decarboxylation to succinate. Located in axon; cytoplasm; and synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and sensory organ. Used to study epilepsy and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; amphetamine abuse; diabetes mellitus (multiple); drug psychosis; and heroin dependence. Orthologous to human GAD2 (glutamate decarboxylase 2).