Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in inhibitory synapse assembly and regulation of postsynaptic membrane potential. Located in plasma membrane. Is active in GABA-ergic synapse. Is expressed in central nervous system; eye; palatal shelf; and submandibular gland primordium. Used to study idiopathic generalized epilepsy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 19 and idiopathic generalized epilepsy 13. Orthologous to human GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1).