Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables FK506 binding activity; identical protein binding activity; and transmembrane transporter binding activity. Involved in heart trabecula formation and ventricular cardiac muscle tissue morphogenesis. Acts upstream of or within several processes, including T cell proliferation; release of sequestered calcium ion into cytosol; and response to caffeine. Located in sarcoplasmic reticulum membrane. Is active in synapse. Is expressed in several structures, including brain ventricular layer; jaw; orbito-sphenoid; thalamus mantle layer; and ventral grey horn. Used to study Barth syndrome. Orthologous to several human genes including FKBP1A (FKBP prolyl isomerase 1A).