Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable endothelin B receptor binding activity and hormone activity. Involved in several processes, including axon extension; cell tip growth; and prostaglandin biosynthetic process. Acts upstream of or within several processes, including energy homeostasis; lung alveolus development; and positive regulation of smooth muscle contraction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and skeleton. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).