Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including LIM domain binding activity; protein homodimerization activity; and transcription coactivator activity. Contributes to DNA binding activity. Involved in several processes, including negative regulation of erythrocyte differentiation; positive regulation of macromolecule biosynthetic process; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Acts upstream of or within several processes, including cerebellar Purkinje cell differentiation; epithelial structure maintenance; and hair follicle development. Located in cell leading edge and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; eye; and genitourinary system. Used to study nail-patella syndrome. Orthologous to human LDB1 (LIM domain binding 1).