Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables histone H3S10 kinase activity and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including microtubule cytoskeleton organization; positive regulation of oocyte maturation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in axon hillock; microtubule cytoskeleton; and nucleus. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including alimentary system; bone; brain; eye; and genitourinary system. Human ortholog(s) of this gene implicated in colorectal cancer; ovarian cancer; and uterine cancer. Orthologous to human AURKA (aurora kinase A).