Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including amyloid-beta binding activity; protein homodimerization activity; and unfolded protein binding activity. Acts upstream of or within several processes, including lens development in camera-type eye; response to hydrogen peroxide; and tubulin complex assembly. Located in several cellular components, including Z disc; cytosol; and mitochondrion. Is expressed in several structures, including brain; embryo mesenchyme; eye; heart; and musculature. Used to study cataract 16 multiple types and myofibrillar myopathy 2. Human ortholog(s) of this gene implicated in cataract 16 multiple types; dilated cardiomyopathy 1II; fatal infantile hypertonic myofibrillar myopathy; and myofibrillar myopathy 2. Orthologous to human CRYAB (crystallin alpha B).