Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within camera-type eye morphogenesis and endothelial cell proliferation. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in basement membrane and extracellular space. Is expressed in blood vessel; cornea endothelium; genitourinary system; and heart. Used to study Fuchs' endothelial dystrophy. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 2. Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).