Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable molecular adaptor activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in DNA-templated transcription and cellular response to transforming growth factor beta stimulus. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway. Located in basement membrane. Part of collagen type IV trimer. Is expressed in several structures, including blastocyst; eye; genitourinary system; lung; and oral region epithelium. Human ortholog(s) of this gene implicated in atherosclerosis; brain small vessel disease 2; porencephaly; and uterine fibroid. Orthologous to human COL4A2 (collagen type IV alpha 2 chain).