Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including negative regulation of neuroblast proliferation; positive regulation of transcription by RNA polymerase II; and retinal bipolar neuron differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including bladder; central nervous system; eye; and lip. Human ortholog(s) of this gene implicated in blindness and isolated microphthalmia 2. Orthologous to human VSX2 (visual system homeobox 2).