Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled acetylcholine receptor activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within G protein-coupled acetylcholine receptor signaling pathway. Is active in cholinergic synapse. Is expressed in several structures, including alimentary system; central nervous system; heart; sublingual gland primordium; and trigeminal nerve. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).