Automated description from the Alliance of Genome Resources (Release 5.3.0)
Predicted to enable lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of cytokine production; and positive regulation of signal transduction. Located in external side of plasma membrane and membrane raft. Is expressed in several structures, including femur; gallbladder; intestine; reproductive system; and telencephalon. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and perinatal necrotizing enterocolitis. Orthologous to human CD14 (CD14 molecule).