Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to be involved in complement activation. Predicted to act upstream of or within complement activation, alternative pathway; complement activation, classical pathway; and killing of cells of another organism. Predicted to be located in extracellular region. Predicted to be part of membrane attack complex. Predicted to be active in extracellular space. Is expressed in brain; liver and biliary system; stomach; and testis. Human ortholog(s) of this gene implicated in type II complement component 8 deficiency. Orthologous to human C8B (complement C8 beta chain).