Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ATP binding activity and proton-transporting ATP synthase activity, rotational mechanism. Acts upstream of or within lipid metabolic process; proton motive force-driven ATP synthesis; and proton transmembrane transport. Located in membrane and mitochondrion. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 22; mitochondrial complex V (ATP synthase) deficiency nuclear type 4A; and mitochondrial complex V (ATP synthase) deficiency nuclear type 4B. Orthologous to human ATP5F1A (ATP synthase F1 subunit alpha).