Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables several functions, including cholesterol transfer activity; high-density lipoprotein particle binding activity; and identical protein binding activity. Acts upstream of or within several processes, including adrenal gland development; cholesterol biosynthetic process; and cholesterol efflux. Located in extracellular space. Is expressed in several structures, including adrenal gland; gonad; gut; liver; and lung. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial visceral amyloidosis; hypolipoproteinemia (multiple); metabolic dysfunction-associated steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1).