Automated description from the Alliance of Genome Resources (Release 7.1.0)
A structural constituent of cytoskeleton. Involved in synapse assembly. Acts upstream of or within hemopoiesis. Located in membrane and postsynaptic density. Is expressed in several structures, including central nervous system; liver; retina; spinal ganglion; and turbinate bone primordium. Used to study hereditary spherocytosis type 1. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and hypertension. Orthologous to human ADD2 (adducin 2).