Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables 2'-deoxyadenosine deaminase activity; adenosine deaminase activity; and zinc ion binding activity. Involved in several processes, including allantoin metabolic process; amide catabolic process; and nucleobase-containing small molecule metabolic process. Acts upstream of or within several processes, including negative regulation of lymphocyte apoptotic process; nucleobase-containing small molecule metabolic process; and positive regulation of lymphocyte activation. Located in cytoplasm. Is active in cytosol. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in asthma; colon cancer; pleural tuberculosis; severe combined immunodeficiency (multiple); and uterine fibroid. Orthologous to human ADA (adenosine deaminase).