Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables acetylcholine binding activity and acetylcholine-gated monoatomic cation-selective channel activity. Acts upstream of or within regulation of membrane potential. Located in plasma membrane. Part of acetylcholine-gated channel complex. Is active in neuromuscular junction and postsynaptic specialization membrane. Is expressed in several structures, including forelimb bud; limb segment; lung; paraxial mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 2A and congenital myasthenic syndrome 2C. Orthologous to human CHRNB1 (cholinergic receptor nicotinic beta 1 subunit).