Automated description from the Alliance of Genome Resources (Release 8.3.0)
Predicted to enable NEDD8 ligase activity; cullin family protein binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including endoplasmic reticulum unfolded protein response; negative regulation of focal adhesion assembly; and protein modification by small protein conjugation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of Cul5-RING ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human RNF7 (ring finger protein 7).
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