Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable NEDD8 ligase activity; cullin family protein binding activity; and ubiquitin protein ligase activity. Predicted to be involved in protein neddylation; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of Cul5-RING ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human RNF7 (ring finger protein 7).