Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in several processes, including GDF15-GFRAL signaling pathway; reduction of food intake in response to dietary excess; and response to metformin. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of neuron apoptotic process; and stress-activated protein kinase signaling cascade. Located in plasma membrane. Orthologous to human GFRAL (GDNF family receptor alpha like).