Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables phosphatidylinositol binding activity; protein kinase binding activity; and signaling adaptor activity. Involved in enzyme-linked receptor protein signaling pathway; positive regulation of Rac protein signal transduction; and positive regulation of skeletal muscle acetylcholine-gated channel clustering. Acts upstream of or within neuromuscular junction development; positive regulation of protein phosphorylation; and receptor clustering. Located in plasma membrane. Is active in neuromuscular junction and postsynaptic membrane. Is expressed in several structures, including central nervous system; heart; musculature; and testis. Used to study congenital myasthenic syndrome 10. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10 and fetal akinesia deformation sequence syndrome 3. Orthologous to human DOK7 (docking protein 7).