Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in actin cytoskeleton organization; modulation of chemical synaptic transmission; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Is active in several cellular components, including photoreceptor ribbon synapse; postsynaptic density; and presynaptic active zone cytoplasmic component. Is expressed in brain. Used to study non-syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 1. Orthologous to human IQSEC2 (IQ motif and Sec7 domain ArfGEF 2).