Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables cardiolipin binding activity and wide pore channel activity. Involved in several processes, including hair follicle development; positive regulation of interleukin-1 beta production; and pyroptosis. Acts upstream of or within several processes, including hair follicle morphogenesis; negative regulation of timing of anagen; and regulation of signal transduction. Located in several cellular components, including cytosol; mitochondrion; and nucleus. Is active in membrane. Is expressed in foregut; hair root sheath; and hair shaft. Orthologous to human GSDMA (gasdermin A).