Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable GTPase activator activity; guanyl-nucleotide exchange factor activity; and phospholipid binding activity. Acts upstream of or within several processes, including neutrophil chemotaxis; positive regulation of substrate adhesion-dependent cell spreading; and reactive oxygen species metabolic process. Predicted to be located in several cellular components, including dendritic shaft; growth cone; and perinuclear region of cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including liver; nervous system; palatal shelf; skeleton; and testis. Used to study autism spectrum disorder. Orthologous to human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1).