Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in muscle organ development and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including collagen fibril organization; regulation of gene expression; and tendon development. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; limb; and sensory organ. Orthologous to human MKX (mohawk homeobox).