Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable phosphatidylinositol 3-kinase binding activity and protein-macromolecule adaptor activity. Involved in endosome to lysosome transport. Acts upstream of or within G protein-coupled receptor catabolic process; autophagy; and glucose homeostasis. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Predicted to be active in phagophore assembly site. Is expressed in several structures, including liver; reproductive system; skeletal muscle; stomach; and thymus. Orthologous to human BECN2 (beclin 2).