Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including STAT family protein binding activity; histone H4K91 ubiquitin ligase activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Predicted to be involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of protein localization; and protein ubiquitination. Predicted to act upstream of or within several processes, including DNA repair; chromatin organization; and defense response to symbiont. Predicted to be located in cytosol; lysosome; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to colocalize with early endosome and nucleus. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and oral cavity. Orthologous to human DTX3L (deltex E3 ubiquitin ligase 3L).