Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables ubiquitin protein ligase activity. Involved in protein monoubiquitination and response to denervation involved in regulation of muscle adaptation. Acts upstream of or within cellular response to dexamethasone stimulus; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of gene expression. Predicted to be located in contractile muscle fiber. Predicted to be active in cytoplasm. Is expressed in embryo and heart. Orthologous to human TRIM63 (tripartite motif containing 63).