Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables deSUMOylase activity. Involved in protein desumoylation. Acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of definitive erythrocyte differentiation. Predicted to be located in focal adhesion; nuclear membrane; and nucleoplasm. Predicted to be active in nucleus. Is expressed in embryo and heart. Used to study type 1 diabetes mellitus. Orthologous to human SENP1 (SUMO specific peptidase 1).