Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity and E-box binding activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of neuroinflammatory response; and regulation of cellular biosynthetic process. Acts upstream of or within circadian rhythm and regulation of DNA-templated transcription. Located in cytoplasm; dendritic spine; and nucleus. Is expressed in several structures, including alimentary system; connective tissue; genitourinary system; liver and biliary system; and nervous system. Human ortholog(s) of this gene implicated in brain small vessel disease. Orthologous to human NR1D1 (nuclear receptor subfamily 1 group D member 1).