Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in several processes, including cilium assembly; limb development; and regulation of smoothened signaling pathway. Acts upstream of or within several processes, including cilium assembly; hair follicle morphogenesis; and nervous system development. Located in centriole; ciliary transition zone; and cytoplasm. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII. Orthologous to human INTU (inturned planar cell polarity protein).