Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ATP-dependent diacylglycerol kinase activity; GTPase inhibitor activity; and small GTPase binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including chemical synaptic transmission; habituation; and modulation of chemical synaptic transmission. Located in perinuclear region of cytoplasm and presynapse. Part of guanyl-nucleotide exchange factor complex. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in cerebral cortex; cerebral cortex mantle layer; and cerebral cortex marginal layer. Orthologous to human DGKI (diacylglycerol kinase iota).