Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables tubulin-glutamic acid ligase activity. Acts upstream of or within several processes, including cerebellar Purkinje cell differentiation; mucociliary clearance; and regulation of blastocyst development. Located in ciliary basal body. Is expressed in 1-cell stage embryo; 8-cell stage embryo; blastocyst; and cortical plate. Used to study primary ciliary dyskinesia. Orthologous to human TTLL1 (TTL family tubulin polyglutamylase complex subunit L1).