Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables actin filament binding activity; microfilament motor activity; and protein serine/threonine kinase activity. Involved in auditory receptor cell stereocilium organization; cochlea morphogenesis; and regulation of actin filament length. Acts upstream of or within several processes, including positive regulation of filopodium assembly; protein phosphorylation; and sensory perception of sound. Located in filopodium tip and photoreceptor inner segment. Is active in stereocilium tip. Is expressed in cochlea and metanephros. Used to study autosomal recessive nonsyndromic deafness 30. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 90 and autosomal recessive nonsyndromic deafness 30. Orthologous to human MYO3A (myosin IIIA).
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