Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables chromatin binding activity and transcription corepressor activity. Acts upstream of or within inner ear development; kidney development; and positive regulation of transcription by RNA polymerase II. Located in several cellular components, including cytoskeleton; cytosol; and nucleus. Is expressed in brain; heart; liver; lung; and metanephros. Used to study autosomal recessive polycystic kidney disease. Orthologous to human CYS1 (cystin 1).