Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glucose:proton symporter activity and sucrose:proton symporter activity. Involved in developmental pigmentation; lysosomal lumen pH elevation; and melanin biosynthetic process from tyrosine. Acts upstream of or within sucrose transport. Predicted to be located in melanosome membrane. Predicted to be active in membrane. Is expressed in brain; embryo ectoderm; eye; mesenchyme derived from neural crest; and skin. Used to study oculocutaneous albinism. Human ortholog(s) of this gene implicated in oculocutaneous albinism type IV and pigmentation disease. Orthologous to human SLC45A2 (solute carrier family 45 member 2).