Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 1-acylglycerol-3-phosphate O-acyltransferase activity; anion binding activity; and triglyceride lipase activity. Involved in glycerolipid metabolic process; long-chain fatty acid metabolic process; and response to dietary excess. Located in lipid droplet and membrane. Is expressed in left lung; olfactory epithelium; and right lung. Used to study metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in coronary artery disease; liver disease (multiple); and type 2 diabetes mellitus. Orthologous to human PNPLA3 (patatin like phospholipase domain containing 3).