Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable structural molecule activity. Predicted to be involved in several processes, including bicellular tight junction assembly; positive regulation of calcium ion transport; and transepithelial transport. Predicted to act upstream of or within monoatomic ion transport. Located in bicellular tight junction. Is expressed in metanephros and stomach. Used to study renal hypomagnesemia 3. Human ortholog(s) of this gene implicated in renal hypomagnesemia 3 and renal tubular transport disease. Orthologous to human CLDN16 (claudin 16).